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Duan, Lei
One or more keywords matched the following items that are connected to
Duan, Lei
Item Type
Name
Concept
Tumor Suppressor Protein p53
Academic Article
Increasing cisplatin sensitivity by schedule-dependent inhibition of AKT and Chk1.
Academic Article
p53-regulated autophagy is controlled by glycolysis and determines cell fate.
Academic Article
Modeling the Etiology of p53-mutated Cancer Cells.
Academic Article
Crosstalk between the IGF-1R/AKT/mTORC1 pathway and the tumor suppressors p53 and p27 determines cisplatin sensitivity and limits the effectiveness of an IGF-1R pathway inhibitor.
Academic Article
p53 promotes AKT and SP1-dependent metabolism through the pentose phosphate pathway that inhibits apoptosis in response to Nutlin-3a.
Academic Article
Alpha ketoglutarate levels, regulated by p53 and OGDH, determine autophagy and cell fate/apoptosis in response to Nutlin-3a.
Academic Article
The histone demethylase JMJD2B is critical for p53-mediated autophagy and survival in Nutlin-treated cancer cells.
Academic Article
RBL2/DREAM-mediated repression of the Aurora kinase A/B pathway determines therapy responsiveness and outcome in p53 WT NSCLC.
Academic Article
CSE1L is a negative regulator of the RB-DREAM pathway in p53 wild-type NSCLC and can be targeted using an HDAC1/2 inhibitor.
Search Criteria
Tumor Suppressor Protein p53